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Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts

Perspectives on whether the functions of MAS, a G protein-coupled receptor, are beneficial or deleterious in the heart remain controversial. MAS gene knockout reduces coronary vasodilatation leading to ischemic injury. G protein signaling activated by MAS has been implicated in progression of adapti...

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Detalles Bibliográficos
Autores principales: Chatterjee, Arunachal, Barnard, John, Moravec, Christine, Desnoyer, Russell, Tirupula, Kalyan, Karnik, Sadashiva S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747466/
https://www.ncbi.nlm.nih.gov/pubmed/29287092
http://dx.doi.org/10.1371/journal.pone.0190217