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Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation

Multiciliated cells of the airways, brain ventricles, and female reproductive tract provide the motive force for mucociliary clearance, cerebrospinal fluid circulation, and ovum transport. Despite their clear importance to human biology and health, the molecular mechanisms underlying multiciliated c...

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Detalles Bibliográficos
Autores principales: Siller, Saul S., Sharma, Himanshu, Li, Shuai, Yang, June, Zhang, Yong, Holtzman, Michael J., Winuthayanon, Wipawee, Colognato, Holly, Holdener, Bernadette C., Li, Feng-Qian, Takemaru, Ken-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747467/
https://www.ncbi.nlm.nih.gov/pubmed/29244804
http://dx.doi.org/10.1371/journal.pgen.1007128