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Loss of TLR4 in mouse Müller cells inhibits both MyD88-dependent and –independent signaling

Müller cells are key to metabolic and ionic regulation in the retina. They also produce a number of inflammatory mediators and are significantly affected in diabetic retinopathy. To investigate the role of toll-like receptor 4 (TLR4) in retinal Müller cells, we crossed TLR4 floxed with PDGFRα-Cre mi...

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Detalles Bibliográficos
Autores principales: Liu, Li, Steinle, Jena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747480/
https://www.ncbi.nlm.nih.gov/pubmed/29287085
http://dx.doi.org/10.1371/journal.pone.0190253