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The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation

Hepadnavirus covalently closed circular (ccc) DNA is the bona fide viral transcription template, which plays a pivotal role in viral infection and persistence. Upon infection, the non-replicative cccDNA is converted from the incoming and de novo synthesized viral genomic relaxed circular (rc) DNA, p...

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Detalles Bibliográficos
Autores principales: Long, Quanxin, Yan, Ran, Hu, Jieli, Cai, Dawei, Mitra, Bidisha, Kim, Elena S., Marchetti, Alexander, Zhang, Hu, Wang, Soujuan, Liu, Yuanjie, Huang, Ailong, Guo, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747486/
https://www.ncbi.nlm.nih.gov/pubmed/29287110
http://dx.doi.org/10.1371/journal.ppat.1006784