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Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses
The host innate immune response mediated by type I interferon (IFN) and the resulting up-regulation of hundreds of interferon-stimulated genes (ISGs) provide an immediate barrier to virus infection. Studies of the type I ‘interferome’ have mainly been carried out at a single species level, often lac...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747502/ https://www.ncbi.nlm.nih.gov/pubmed/29253856 http://dx.doi.org/10.1371/journal.pbio.2004086 |