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Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses

The host innate immune response mediated by type I interferon (IFN) and the resulting up-regulation of hundreds of interferon-stimulated genes (ISGs) provide an immediate barrier to virus infection. Studies of the type I ‘interferome’ have mainly been carried out at a single species level, often lac...

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Detalles Bibliográficos
Autores principales: Shaw, Andrew E., Hughes, Joseph, Gu, Quan, Behdenna, Abdelkader, Singer, Joshua B., Dennis, Tristan, Orton, Richard J., Varela, Mariana, Gifford, Robert J., Wilson, Sam J., Palmarini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747502/
https://www.ncbi.nlm.nih.gov/pubmed/29253856
http://dx.doi.org/10.1371/journal.pbio.2004086