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Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition

Chronic low dose inorganic arsenic exposure causes cells to take on an epithelial-to-mesenchymal phenotype, which is a crucial process in carcinogenesis. Inorganic arsenic is not a mutagen and thus epigenetic alterations have been implicated in this process. Indeed, during the epithelial-to-mesenchy...

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Detalles Bibliográficos
Autores principales: Eckstein, Meredith, Rea, Matthew, Fondufe-Mittendorf, Yvonne N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747965/
https://www.ncbi.nlm.nih.gov/pubmed/28336213
http://dx.doi.org/10.1016/j.taap.2017.03.017