Obesity Enhances the Conversion of Adipose-Derived Stromal/Stem Cells into Carcinoma-Associated Fibroblast Leading to Cancer Cell Proliferation and Progression to an Invasive Phenotype

Obesity is associated with enhanced tumor growth and progression. Within the adipose tissue are adipose-derived stromal/stem cells (ASCs) that have been shown to convert into carcinoma-associated fibroblast (CAFs) in the presence of tumor-derived factors. However, the impact of obesity on the ASCs a...

Descripción completa

Detalles Bibliográficos
Autores principales: Strong, Amy L., Pei, Dorothy T., Hurst, Christian G., Gimble, Jeffrey M., Burow, Matthew E., Bunnell, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748106/
https://www.ncbi.nlm.nih.gov/pubmed/29527228
http://dx.doi.org/10.1155/2017/9216502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748106/
https://www.ncbi.nlm.nih.gov/pubmed/29527228
http://dx.doi.org/10.1155/2017/9216502

Ejemplares similares