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Activation State-Dependent Substrate Gating in Ca(2+)/Calmodulin-Dependent Protein Kinase II
Calcium/calmodulin-dependent protein kinase II (CaMKII) is highly concentrated in the brain where its activation by the Ca(2+) sensor CaM, multivalent structure, and complex autoregulatory features make it an ideal translator of Ca(2+) signals created by different patterns of neuronal activity. We p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748111/ https://www.ncbi.nlm.nih.gov/pubmed/29391954 http://dx.doi.org/10.1155/2017/9601046 |