Cargando…

Interferon-beta represses cancer stem cell properties in triple-negative breast cancer

Triple-negative breast cancer (TNBC), the deadliest form of this disease, lacks a targeted therapy. TNBC tumors that fail to respond to chemotherapy are characterized by a repressed IFN/signal transducer and activator of transcription (IFN/STAT) gene signature and are often enriched for cancer stem...

Descripción completa

Detalles Bibliográficos
Autores principales: Doherty, Mary R., Cheon, HyeonJoo, Junk, Damian J., Vinayak, Shaveta, Varadan, Vinay, Telli, Melinda L., Ford, James M., Stark, George R., Jackson, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748193/
https://www.ncbi.nlm.nih.gov/pubmed/29229854
http://dx.doi.org/10.1073/pnas.1713728114