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Interferon-beta represses cancer stem cell properties in triple-negative breast cancer
Triple-negative breast cancer (TNBC), the deadliest form of this disease, lacks a targeted therapy. TNBC tumors that fail to respond to chemotherapy are characterized by a repressed IFN/signal transducer and activator of transcription (IFN/STAT) gene signature and are often enriched for cancer stem...
Autores principales: | Doherty, Mary R., Cheon, HyeonJoo, Junk, Damian J., Vinayak, Shaveta, Varadan, Vinay, Telli, Melinda L., Ford, James M., Stark, George R., Jackson, Mark W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748193/ https://www.ncbi.nlm.nih.gov/pubmed/29229854 http://dx.doi.org/10.1073/pnas.1713728114 |
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