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Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice

A single-nucleotide polymorphism in the human arylamine N-acetyltransferase 2 (Nat2) gene has recently been identified as associated with insulin resistance in humans. To understand the cellular and molecular mechanisms by which alterations in Nat2 activity might cause insulin resistance, we examine...

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Detalles Bibliográficos
Autores principales: Camporez, João Paulo, Wang, Yongliang, Faarkrog, Kasper, Chukijrungroat, Natsasi, Petersen, Kitt Falk, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748223/
https://www.ncbi.nlm.nih.gov/pubmed/29237750
http://dx.doi.org/10.1073/pnas.1716990115