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EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats

OBJECTIVE: To observe the protective effect of epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF-κB signaling pathway. METHODS: Rat models of ulcerative colitis were established by giving DSS. EGCG (50 mg/kg...

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Detalles Bibliográficos
Autores principales: Bing, Xue, Xuelei, Liu, Wanwei, Dong, Linlang, Liang, Keyan, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748319/
https://www.ncbi.nlm.nih.gov/pubmed/29404307
http://dx.doi.org/10.1155/2017/3057268