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Increased Abundance of Plasmacytoid Dendritic Cells and Interferon-Alpha Induces Plasma Cell Differentiation in Patients of IgA Nephropathy

The roles of pDC and IFN-α have not been well defined in IgA nephropathy (IgAN). In this study, we investigated the abundance of pDCs and IFN-α in IgAN patients and the response of peripheral blood mononuclear cells (PBMCs) after stimulation of the pDC-preferred TLR9 ligand CpG2216. The effects of I...

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Detalles Bibliográficos
Autores principales: Zheng, Nuoyan, Wang, Bing, Fan, Jinjin, Luo, Ning, Kong, Qingyu, Ye, Hongjian, Zhang, Jiqin, Ming, Hongyan, Yu, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748321/
https://www.ncbi.nlm.nih.gov/pubmed/29403161
http://dx.doi.org/10.1155/2017/4532409