Population pharmacokinetics of treosulfan and development of a limited sampling strategy in children prior to hematopoietic stem cell transplantation

PURPOSE: There is an increasing interest in use of treosulfan (TREO), a structural analogue of busulfan, as an agent in conditioning regimens prior to hematopoietic stem cell transplantation (HSCT), both in pediatric and adult populations. The aim of this study was to develop a population pharmacoki...

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Detalles Bibliográficos
Autores principales: Danielak, Dorota, Twardosz, Jadwiga, Kasprzyk, Anna, Wachowiak, Jacek, Kałwak, Krzysztof, Główka, Franciszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748442/
https://www.ncbi.nlm.nih.gov/pubmed/28975382
http://dx.doi.org/10.1007/s00228-017-2344-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748442/
https://www.ncbi.nlm.nih.gov/pubmed/28975382
http://dx.doi.org/10.1007/s00228-017-2344-x

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