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Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation

The methylotrophic yeast Komagataella phaffii (Pichia pastoris) is homothallic and has been reported to switch mating type by an ancient inversion mechanism. Two mating-type (MAT) loci include homologs of the MATa and MATα transcription factor genes, with the expression from one locus downregulated...

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Detalles Bibliográficos
Autores principales: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748462/
https://www.ncbi.nlm.nih.gov/pubmed/29061733
http://dx.doi.org/10.1128/MCB.00398-17