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X‐linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery

Acute myeloid leukemia (AML) is an aggressive disease with an increasing incidence and relatively low 5‐year survival rate. Unfortunately, the underlying mechanism of leukemogenesis is poorly known, and there has been little progress in the treatment for AML. Studies have shown that X‐linked inhibit...

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Detalles Bibliográficos
Autores principales: Zhou, Jianbiao, Lu, Xiao, Tan, Tuan Zea, Chng, Wee‐Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748481/
https://www.ncbi.nlm.nih.gov/pubmed/29063676
http://dx.doi.org/10.1002/1878-0261.12146