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A link between the fibroblast growth factor axis and the miR‐16 family reveals potential new treatment combinations in mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive malignancy with very limited therapeutic options. Fibroblast growth factor (FGF) signals play important roles in mesothelioma cell growth. Several FGFs and FGF receptors (FGFRs) are predicted targets of the miR‐15/16 family, which is downregulate...

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Detalles Bibliográficos
Autores principales: Schelch, Karin, Kirschner, Michaela B., Williams, Marissa, Cheng, Yuen Y., van Zandwijk, Nico, Grusch, Michael, Reid, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748487/
https://www.ncbi.nlm.nih.gov/pubmed/29094504
http://dx.doi.org/10.1002/1878-0261.12150