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TLR4 Signaling Pathway Modulators as Potential Therapeutics in Inflammation and Sepsis

Toll-Like Receptor 4 (TLR4) signal pathway plays an important role in initiating the innate immune response and its activation by bacterial endotoxin is responsible for chronic and acute inflammatory disorders that are becoming more and more frequent in developed countries. Modulation of the TLR4 pa...

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Detalles Bibliográficos
Autores principales: Kuzmich, Nikolay N., Sivak, Konstantin V., Chubarev, Vladimir N., Porozov, Yury B., Savateeva-Lyubimova, Tatiana N., Peri, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748601/
https://www.ncbi.nlm.nih.gov/pubmed/28976923
http://dx.doi.org/10.3390/vaccines5040034