Immortalized Muscle Cell Model to Test the Exon Skipping Efficacy for Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a lethal genetic disorder that most commonly results from mutations disrupting the reading frame of the dystrophin (DMD) gene. Among the therapeutic approaches employed, exon skipping using antisense oligonucleotides (AOs) is one of the most promising strategies....

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Detalles Bibliográficos
Autores principales: Nguyen, Quynh, Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748625/
https://www.ncbi.nlm.nih.gov/pubmed/29035327
http://dx.doi.org/10.3390/jpm7040013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748625/
https://www.ncbi.nlm.nih.gov/pubmed/29035327
http://dx.doi.org/10.3390/jpm7040013

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