Molecular Docking and 3D-Pharmacophore Modeling to Study the Interactions of Chalcone Derivatives with Estrogen Receptor Alpha

Tamoxifen is the most frequently used anti-estrogen adjuvant treatment for estrogen receptor-positive breast cancer. However, it is associated with an increased risk of several serious side–effects, such as uterine cancer, stroke, and pulmonary embolism. The 2′,4′-dihydroxy-6-methoxy-3,5-dimethylcha...

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Detalles Bibliográficos
Autores principales: Muchtaridi, Muchtaridi, Syahidah, Hasna Nur, Subarnas, Anas, Yusuf, Muhammad, Bryant, Sharon D., Langer, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748638/
https://www.ncbi.nlm.nih.gov/pubmed/29035298
http://dx.doi.org/10.3390/ph10040081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748638/
https://www.ncbi.nlm.nih.gov/pubmed/29035298
http://dx.doi.org/10.3390/ph10040081

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