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Propagation of Fibrillar Structural Forms in Proteins Stopped by Naturally Occurring Short Polypeptide Chain Fragments

Amyloids characterized by unbounded growth of fibrillar structures cause many pathological processes. Such unbounded propagation is due to the presence of a propagating hydrophobicity field around the fibril’s main axis, preventing its closure (unlike in globular proteins). Interestingly, similar fr...

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Detalles Bibliográficos
Autores principales: Roterman, Irena, Banach, Mateusz, Konieczny, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748646/
https://www.ncbi.nlm.nih.gov/pubmed/29144442
http://dx.doi.org/10.3390/ph10040089