Early Gabapentin Treatment during the Latency Period Increases Convulsive Threshold, Reduces Microglial Activation and Macrophage Infiltration in the Lithium-Pilocarpine Model of Epilepsy

The lithium-pilocarpine model of epilepsy reproduces several features of temporal lobe epilepsy in humans, including the chronological timeline of an initial latency period followed by the development of spontaneous seizures. Epilepsy therapies in humans are implemented, as a rule, after the onset o...

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Detalles Bibliográficos
Autores principales: Rossi, Alicia, Murta, Veronica, Auzmendi, Jerónimo, Ramos, Alberto Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748648/
https://www.ncbi.nlm.nih.gov/pubmed/29182533
http://dx.doi.org/10.3390/ph10040093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748648/
https://www.ncbi.nlm.nih.gov/pubmed/29182533
http://dx.doi.org/10.3390/ph10040093

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