MicroRNA-132 Negatively Regulates Palmitate-Induced NLRP3 Inflammasome Activation through FOXO3 Down-Regulation in THP-1 Cells

Saturated fatty acids were proposed to activate the NLRP3 inflammasome, a molecular platform that mediates the processing of interleukin (IL)-1β and IL-18. However, the mechanisms underlying the miRNA-mediated regulation of palmitate (PA)-induced inflammasome activation are unclear. We examined the...

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Detalles Bibliográficos
Autores principales: Byeon, Hye-Eun, Jeon, Ja Young, Kim, Hae Jin, Kim, Dae Jung, Lee, Kwan-Woo, Kang, Yup, Han, Seung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748820/
https://www.ncbi.nlm.nih.gov/pubmed/29258239
http://dx.doi.org/10.3390/nu9121370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748820/
https://www.ncbi.nlm.nih.gov/pubmed/29258239
http://dx.doi.org/10.3390/nu9121370

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