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Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin

The transcription factor NRF2 (nuclear factor-E2-related factor 2) orchestrates major cellular defense mechanisms including phase-II detoxification, inflammatory signaling, DNA repair, and antioxidant response. Recent studies strongly suggest a protective role of NRF2-mediated gene expression in the...

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Detalles Bibliográficos
Autores principales: Rojo de la Vega, Montserrat, Krajisnik, Andrea, Zhang, Donna D., Wondrak, Georg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748821/
https://www.ncbi.nlm.nih.gov/pubmed/29258247
http://dx.doi.org/10.3390/nu9121371