Synthesis and Biological Evaluation of Novel Hybrid Molecules Containing Purine, Coumarin and Isoxazoline or Isoxazole Moieties

INTRODUCTION: The 1,3-dipolar cycloaddition reactions of nitrile oxides formed in situ (in the presence of NCS and Et(3)N) from the oximes of (purin-9-yl)acetaldehyde or (coumarinyloxy)acetaldehyde with allyloxycoumarins or 9-allylpurines, respectively resulted in 3,5-disubstituted isoxazolines. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Kallitsakis, Michael G., Carotti, Angelo, Catto, Marco, Peperidou, Aikaterini, Hadjipavlou-Litina, Dimitra J., Litinas, Konstantinos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748833/
https://www.ncbi.nlm.nih.gov/pubmed/29387274
http://dx.doi.org/10.2174/1874104501711010196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748833/
https://www.ncbi.nlm.nih.gov/pubmed/29387274
http://dx.doi.org/10.2174/1874104501711010196

Ejemplares similares