Mechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks

Derailment of the PI3K-AGC protein kinase signalling network contributes to many human diseases including cancer. Recent work has revealed that the poorly studied AGC kinase family member, SGK3, promotes resistance to cancer therapies that target the Class 1 PI3K pathway, by substituting for loss of...

Descripción completa

Detalles Bibliográficos
Autores principales: Malik, Nazma, Macartney, Thomas, Hornberger, Annika, Anderson, Karen E., Tovell, Hannah, Prescott, Alan R., Alessi, Dario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748840/
https://www.ncbi.nlm.nih.gov/pubmed/29150437
http://dx.doi.org/10.1042/BCJ20170650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748840/
https://www.ncbi.nlm.nih.gov/pubmed/29150437
http://dx.doi.org/10.1042/BCJ20170650

Ejemplares similares