Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

Antibodies against the central repeat of the Plasmodium falciparum (Pf) circumsporozoite protein (CSP) inhibit parasite activity and correlate with protection from malaria. However, the humoral response to the PfCSP C terminus (C-PfCSP) is less well characterized. Here, we describe B cell responses...

Descripción completa

Detalles Bibliográficos
Autores principales: Scally, Stephen W., Murugan, Rajagopal, Bosch, Alexandre, Triller, Gianna, Costa, Giulia, Mordmüller, Benjamin, Kremsner, Peter G., Sim, B. Kim Lee, Hoffman, Stephen L., Levashina, Elena A., Wardemann, Hedda, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748854/
https://www.ncbi.nlm.nih.gov/pubmed/29167197
http://dx.doi.org/10.1084/jem.20170869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748854/
https://www.ncbi.nlm.nih.gov/pubmed/29167197
http://dx.doi.org/10.1084/jem.20170869

Ejemplares similares