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Major Developments in the Design of Inhibitors along the Kynurenine Pathway

Disrupted kynurenine pathway (KP) metabolism has been implicated in the progression of neurodegenerative disease, psychiatric disorders and cancer. Modulation of enzyme activity along this pathway may therefore offer potential new therapeutic strategies for these conditions. Considering their promin...

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Detalles Bibliográficos
Autores principales: Jacobs, Kelly R., Castellano-González, Gloria, Guillemin, Gilles J., Lovejoy, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748880/
https://www.ncbi.nlm.nih.gov/pubmed/28464785
http://dx.doi.org/10.2174/0929867324666170502123114