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Major Developments in the Design of Inhibitors along the Kynurenine Pathway
Disrupted kynurenine pathway (KP) metabolism has been implicated in the progression of neurodegenerative disease, psychiatric disorders and cancer. Modulation of enzyme activity along this pathway may therefore offer potential new therapeutic strategies for these conditions. Considering their promin...
Autores principales: | Jacobs, Kelly R., Castellano-González, Gloria, Guillemin, Gilles J., Lovejoy, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748880/ https://www.ncbi.nlm.nih.gov/pubmed/28464785 http://dx.doi.org/10.2174/0929867324666170502123114 |
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