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Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model

BACKGROUND: Disseminated tumor cells (DTCs) found in the bone marrow (BM) of patients with breast cancer portend a poor prognosis and are thought to be intermediaries in the metastatic process. To assess the clinical relevance of a mouse model for identifying possible prognostic and predictive bioma...

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Detalles Bibliográficos
Autores principales: Pillai, Sreeraj G., Li, Shunqiang, Siddappa, Chidananda M., Ellis, Matthew J, Watson, Mark A., Aft, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748947/
https://www.ncbi.nlm.nih.gov/pubmed/29291741
http://dx.doi.org/10.1186/s13058-017-0927-1