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Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model
BACKGROUND: Disseminated tumor cells (DTCs) found in the bone marrow (BM) of patients with breast cancer portend a poor prognosis and are thought to be intermediaries in the metastatic process. To assess the clinical relevance of a mouse model for identifying possible prognostic and predictive bioma...
Autores principales: | Pillai, Sreeraj G., Li, Shunqiang, Siddappa, Chidananda M., Ellis, Matthew J, Watson, Mark A., Aft, Rebecca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748947/ https://www.ncbi.nlm.nih.gov/pubmed/29291741 http://dx.doi.org/10.1186/s13058-017-0927-1 |
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