Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions

BACKGROUND: Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time relative to the needs of the analysis, and need to be compar...

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Detalles Bibliográficos
Autores principales: Vernon, Ian, Liu, Junli, Goldstein, Michael, Rowe, James, Topping, Jen, Lindsey, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748965/
https://www.ncbi.nlm.nih.gov/pubmed/29291750
http://dx.doi.org/10.1186/s12918-017-0484-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748965/
https://www.ncbi.nlm.nih.gov/pubmed/29291750
http://dx.doi.org/10.1186/s12918-017-0484-3

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