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Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis

There is remarkable redundancy between the Cyclin–Cdk complexes that comprise the cell cycle machinery. None of the mammalian A-, D-, or E-type cyclins are required in development until implantation, and only Cdk1 is essential for early cell divisions. Cyclin B1 is essential for development, but whe...

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Detalles Bibliográficos
Autores principales: Strauss, Bernhard, Harrison, Andrew, Coelho, Paula Almeida, Yata, Keiko, Zernicka-Goetz, Magdalena, Pines, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748970/
https://www.ncbi.nlm.nih.gov/pubmed/29074707
http://dx.doi.org/10.1083/jcb.201612147