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Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis
There is remarkable redundancy between the Cyclin–Cdk complexes that comprise the cell cycle machinery. None of the mammalian A-, D-, or E-type cyclins are required in development until implantation, and only Cdk1 is essential for early cell divisions. Cyclin B1 is essential for development, but whe...
Autores principales: | Strauss, Bernhard, Harrison, Andrew, Coelho, Paula Almeida, Yata, Keiko, Zernicka-Goetz, Magdalena, Pines, Jonathon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748970/ https://www.ncbi.nlm.nih.gov/pubmed/29074707 http://dx.doi.org/10.1083/jcb.201612147 |
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