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p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1

Inflammation and autophagy are two critical cellular processes. The relationship between these two processes is complex and includes the suppression of inflammation by autophagy. However, the signaling mechanisms that relieve this autophagy-mediated inhibition of inflammation to permit a beneficial...

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Detalles Bibliográficos
Autores principales: He, Yingli, She, Hua, Zhang, Ting, Xu, Haidong, Cheng, Lihong, Yepes, Manuel, Zhao, Yingren, Mao, Zixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748971/
https://www.ncbi.nlm.nih.gov/pubmed/29196462
http://dx.doi.org/10.1083/jcb.201701049