Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells

The nonreceptor tyrosine kinase Pyk2 is highly expressed in invasive breast cancer, but the mechanism by which it potentiates tumor cell invasiveness is unclear at present. Using high-throughput protein array screening and bioinformatic analysis, we identified cortactin as a novel substrate and inte...

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Detalles Bibliográficos
Autores principales: Genna, Alessandro, Lapetina, Stefanie, Lukic, Nikola, Twafra, Shams, Meirson, Tomer, Sharma, Ved P., Condeelis, John S., Gil-Henn, Hava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748976/
https://www.ncbi.nlm.nih.gov/pubmed/29133485
http://dx.doi.org/10.1083/jcb.201702184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748976/
https://www.ncbi.nlm.nih.gov/pubmed/29133485
http://dx.doi.org/10.1083/jcb.201702184

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