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MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion

Extrusion of apoptotic cells from epithelial tissues requires orchestrated morphological rearrangements of the apoptotic cell and its neighbors. However, the connections between the apoptotic cascade and events leading to extrusion are not fully understood. Here, we characterize an apoptotic extrusi...

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Detalles Bibliográficos
Autores principales: Gagliardi, Paolo Armando, Somale, Desiana, Puliafito, Alberto, Chiaverina, Giulia, di Blasio, Laura, Oneto, Michele, Bianchini, Paolo, Bussolino, Federico, Primo, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748977/
https://www.ncbi.nlm.nih.gov/pubmed/29162624
http://dx.doi.org/10.1083/jcb.201703044