Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore–microtubule dynamics

Precise regulation of kinetochore–microtubule attachments is essential for successful chromosome segregation. Central to this regulation is Aurora B kinase, which phosphorylates kinetochore substrates to promote microtubule turnover. A critical target of Aurora B is the N-terminal “tail” domain of H...

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Detalles Bibliográficos
Autores principales: DeLuca, Keith F., Meppelink, Amanda, Broad, Amanda J., Mick, Jeanne E., Peersen, Olve B., Pektas, Sibel, Lens, Susanne M.A., DeLuca, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748988/
https://www.ncbi.nlm.nih.gov/pubmed/29187526
http://dx.doi.org/10.1083/jcb.201707160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748988/
https://www.ncbi.nlm.nih.gov/pubmed/29187526
http://dx.doi.org/10.1083/jcb.201707160

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