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Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore–microtubule dynamics

Precise regulation of kinetochore–microtubule attachments is essential for successful chromosome segregation. Central to this regulation is Aurora B kinase, which phosphorylates kinetochore substrates to promote microtubule turnover. A critical target of Aurora B is the N-terminal “tail” domain of H...

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Detalles Bibliográficos
Autores principales:	DeLuca, Keith F., Meppelink, Amanda, Broad, Amanda J., Mick, Jeanne E., Peersen, Olve B., Pektas, Sibel, Lens, Susanne M.A., DeLuca, Jennifer G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748988/ https://www.ncbi.nlm.nih.gov/pubmed/29187526 http://dx.doi.org/10.1083/jcb.201707160

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