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Pathways of cellular proteostasis in aging and disease

Ensuring cellular protein homeostasis, or proteostasis, requires precise control of protein synthesis, folding, conformational maintenance, and degradation. A complex and adaptive proteostasis network coordinates these processes with molecular chaperones of different classes and their regulators fun...

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Detalles Bibliográficos
Autores principales: Klaips, Courtney L., Jayaraj, Gopal Gunanathan, Hartl, F. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748993/
https://www.ncbi.nlm.nih.gov/pubmed/29127110
http://dx.doi.org/10.1083/jcb.201709072