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Pathways of cellular proteostasis in aging and disease
Ensuring cellular protein homeostasis, or proteostasis, requires precise control of protein synthesis, folding, conformational maintenance, and degradation. A complex and adaptive proteostasis network coordinates these processes with molecular chaperones of different classes and their regulators fun...
Autores principales: | Klaips, Courtney L., Jayaraj, Gopal Gunanathan, Hartl, F. Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748993/ https://www.ncbi.nlm.nih.gov/pubmed/29127110 http://dx.doi.org/10.1083/jcb.201709072 |
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