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Molecular moieties masking Ca(2+)-dependent facilitation of voltage-gated Ca(v)2.2 Ca(2+) channels
Voltage-gated Ca(v)2.1 (P/Q-type) Ca(2+) channels undergo Ca(2+)-dependent inactivation (CDI) and facilitation (CDF), both of which contribute to short-term synaptic plasticity. Both CDI and CDF are mediated by calmodulin (CaM) binding to sites in the C-terminal domain of the Ca(v)2.1 α(1) subunit,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749111/ https://www.ncbi.nlm.nih.gov/pubmed/29208674 http://dx.doi.org/10.1085/jgp.201711841 |