Molecular moieties masking Ca(2+)-dependent facilitation of voltage-gated Ca(v)2.2 Ca(2+) channels

Voltage-gated Ca(v)2.1 (P/Q-type) Ca(2+) channels undergo Ca(2+)-dependent inactivation (CDI) and facilitation (CDF), both of which contribute to short-term synaptic plasticity. Both CDI and CDF are mediated by calmodulin (CaM) binding to sites in the C-terminal domain of the Ca(v)2.1 α(1) subunit,...

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Detalles Bibliográficos
Autores principales: Thomas, Jessica R., Hagen, Jussara, Soh, Daniel, Lee, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749111/
https://www.ncbi.nlm.nih.gov/pubmed/29208674
http://dx.doi.org/10.1085/jgp.201711841

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