Voltage modulates halothane-triggered Ca(2+) release in malignant hyperthermia-susceptible muscle

Malignant hyperthermia (MH) is a fatal hypermetabolic state that may occur during general anesthesia in susceptible individuals. It is often caused by mutations in the ryanodine receptor RyR1 that favor drug-induced release of Ca(2+) from the sarcoplasmic reticulum. Here, knowing that membrane depol...

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Detalles Bibliográficos
Autores principales: Zullo, Alberto, Textor, Martin, Elischer, Philipp, Mall, Stefan, Alt, Andreas, Klingler, Werner, Melzer, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749113/
https://www.ncbi.nlm.nih.gov/pubmed/29247050
http://dx.doi.org/10.1085/jgp.201711864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749113/
https://www.ncbi.nlm.nih.gov/pubmed/29247050
http://dx.doi.org/10.1085/jgp.201711864

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