In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human disease

Adeno-associated virus (AAV) has shown promising therapeutic efficacy with a good safety profile in a wide range of animal models and human clinical trials. With the advent of clustered regulatory interspaced short palindromic repeat (CRISPR)-based genome-editing technologies, AAV provides one of th...

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Detalles Bibliográficos
Autores principales: Lau, Cia-Hin, Suh, Yousin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749125/
https://www.ncbi.nlm.nih.gov/pubmed/29333255
http://dx.doi.org/10.12688/f1000research.11243.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749125/
https://www.ncbi.nlm.nih.gov/pubmed/29333255
http://dx.doi.org/10.12688/f1000research.11243.1

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