Cargando…
In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human disease
Adeno-associated virus (AAV) has shown promising therapeutic efficacy with a good safety profile in a wide range of animal models and human clinical trials. With the advent of clustered regulatory interspaced short palindromic repeat (CRISPR)-based genome-editing technologies, AAV provides one of th...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000 Research Limited
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749125/ https://www.ncbi.nlm.nih.gov/pubmed/29333255 http://dx.doi.org/10.12688/f1000research.11243.1 |