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Observation of DNA intertwining along authentic budding yeast chromosomes

DNA replication of circular genomes generates physically interlinked or catenated sister DNAs. These are resolved through transient DNA fracture by type II topoisomerases to permit chromosome segregation during cell division. Topoisomerase II is similarly required for linear chromosome segregation,...

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Detalles Bibliográficos
Autores principales: Mariezcurrena, Ainhoa, Uhlmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749163/
https://www.ncbi.nlm.nih.gov/pubmed/29208645
http://dx.doi.org/10.1101/gad.305557.117