Cargando…

Impact of regulatory variation across human iPSCs and differentiated cells

Induced pluripotent stem cells (iPSCs) are an essential tool for studying cellular differentiation and cell types that are otherwise difficult to access. We investigated the use of iPSCs and iPSC-derived cells to study the impact of genetic variation on gene regulation across different cell types an...

Descripción completa

Detalles Bibliográficos
Autores principales: Banovich, Nicholas E., Li, Yang I., Raj, Anil, Ward, Michelle C., Greenside, Peyton, Calderon, Diego, Tung, Po Yuan, Burnett, Jonathan E., Myrthil, Marsha, Thomas, Samantha M., Burrows, Courtney K., Romero, Irene Gallego, Pavlovic, Bryan J., Kundaje, Anshul, Pritchard, Jonathan K., Gilad, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749177/
https://www.ncbi.nlm.nih.gov/pubmed/29208628
http://dx.doi.org/10.1101/gr.224436.117