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H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2

Phosphorylation of histone H3 at serine 10 (H3S10ph) by Aurora kinases plays an important role in mitosis; however, H3S10ph also marks regulatory regions of inducible genes in interphase mammalian cells, implicating mitosis-independent functions. Using the fluorescent ubiquitin-mediated cell cycle i...

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Detalles Bibliográficos
Autores principales: Chen, Carol C.L., Goyal, Preeti, Karimi, Mohammad M., Abildgaard, Marie H., Kimura, Hiroshi, Lorincz, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749181/
https://www.ncbi.nlm.nih.gov/pubmed/29229671
http://dx.doi.org/10.1101/gr.224717.117