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DNA mismatch repair preferentially protects genes from mutation

Mutation is the source of genetic variation and fuels biological evolution. Many mutations first arise as DNA replication errors. These errors subsequently evade correction by cellular DNA repair, for example, by the well-known DNA mismatch repair (MMR) mechanism. Here, we determine the genome-wide...

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Detalles Bibliográficos
Autores principales: Belfield, Eric J., Ding, Zhong Jie, Jamieson, Fiona J.C., Visscher, Anne M., Zheng, Shao Jian, Mithani, Aziz, Harberd, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749183/
https://www.ncbi.nlm.nih.gov/pubmed/29233924
http://dx.doi.org/10.1101/gr.219303.116